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Peptide record

TPDB12747

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12747
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ILGKIWEGKKSLF
Physicochemical Analysis
C74H119N17O17
ARNDCQHMPTYV
K
1518.86
10.32
3
1
6
+2
0.42
0.131
120.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
362.11
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
2
G
0
H
2
I
2
L
3
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 2 L: 2 K: 3 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C74H119N17O17
1518.86
10.32
+2
0.42
0.131
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
250 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
An unprecedented alteration in mode of action of IsCT resulting its translocation into bacterial cytoplasm and inhibition of macromolecular syntheses. | Sci Rep | 2015