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Peptide record

TPDB12741

Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12741
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb iACP-DRLF CAFPdb PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
FAKLLAKLAKKVL
Physicochemical Analysis
C71H127N17O14
RNDCEQGHIMPSTWY
LK
1442.89
11.00
4
0
9
+4
0.15
0.923
165.38
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C71H127N17O14
1442.89
11.00
+4
0.15
0.923
Evidence Records 3 records
Evidence 1 Activity

Activity

LD50
Toxicity
21 µg/mL
Cytotoxic
LD50 | 21 | µg/mL | target cell: Human fibroblasts WI-38

Target

Human fibroblasts WI-38

Source & Reference

NA
DBAASP
Short bioactive peptides | PATENT US 6875744B2 | 2005
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
55 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 55 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Short bioactive peptides | PATENT US 6875744B2 | 2005
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis