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Peptide record

TPDB12691

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12691
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWFRFYRFFYRRR
Physicochemical Analysis
C101H138N30O16
ANDCEQGHILMPSTV
R
2028.40
12.24
6
0
7
+6
-3.21
-1.438
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
8480
418.06
2
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
4
F
0
P
0
S
0
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 4 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 0
Chemical Descriptors
13
C101H138N30O16
2028.40
12.24
+6
-3.21
-1.438
Evidence Records 1 records
Evidence 1 Activity

Activity

<1% Hemolysis
Toxicity
490 µM
Hemolytic Cytotoxic
<1% Hemolysis | 490 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Modified Cysteine-Deleted Tachyplesin (CDT) Analogs as Linear Antimicrobial Peptides: Influence of Chain Length, Positive Charge, and Hydrophobicity on Antimicrobial and Hemolytic Activity | Int J Pept Res Ther | 2014