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Peptide record

TPDB12690

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12690
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GLGALWNVAKSVF
Physicochemical Analysis
C65H100N16O16
RDCEQHIMPTY
AGLV
1361.61
10.10
1
0
8
+1
-2.74
0.962
120.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
403.93
2
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
2
L
1
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 2 K: 1 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
13
C65H100N16O16
1361.61
10.10
+1
-2.74
0.962
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens. | Bioorg Chem | 2019
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
10 %
Hemolytic
Hemolytic_activity: [Ref.31212183] 10% hemolysis at 50 µmol/L, 30% hemolysis at 100 µmol/L for human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Bioorg Chem. 2019 Jun 8 90:103038. doi: 10.1016/j.bioorg.2019.103038.