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Peptide record

TPDB12659

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12659
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLFDIIKKIAEAF
Physicochemical Analysis
C71H113N15O18
RNCQHMPSTWYV
I
1464.77
6.99
2
2
8
-0
1.15
0.869
135.38
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
1
E
0
Q
1
G
0
H
3
I
1
L
2
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 3 L: 1 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C71H113N15O18
1464.77
6.99
-0
1.15
0.869
Evidence Records 6 records
Evidence 1 Activity

Activity

23.5% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
23.5% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2 | Probiotics Antimicrob Proteins | 2019
Evidence 2 Activity

Activity

15.4% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
15.4% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2 | Probiotics Antimicrob Proteins | 2019
Evidence 3 Activity

Activity

12.0% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
12.0% Hemolysis | 64 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2 | Probiotics Antimicrob Proteins | 2019
Evidence 4 Activity

Activity

6.5% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
6.5% Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2 | Probiotics Antimicrob Proteins | 2019
Evidence 5 Activity

Activity

1.2% Hemolysis
Toxicity
16 µg/mL
Hemolytic Cytotoxic
1.2% Hemolysis | 16 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Alanine Scanning Studies of the Antimicrobial Peptide Aurein 1.2 | Probiotics Antimicrob Proteins | 2019
Evidence 6 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis