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Peptide record

TPDB12656

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12656
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ILKKIWKPIKKLF
Physicochemical Analysis
C85H143N19O14
ARNDCEQGHMSTYV
K
1655.19
11.12
5
0
7
+5
0.37
0.146
150.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
332.29
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
2
L
5
K
0
M
1
F
1
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 2 K: 5 M: 0 F: 1 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C85H143N19O14
1655.19
11.12
+5
0.37
0.146
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
0% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The role of the central L- or D-Pro residue on structure and mode of action of a cell-selective alpha-helical IsCT-derived antimicrobial peptide. | Biochem Biophys Res Commun | 2005
Evidence 2 Activity

Activity

HC50
Toxicity
400 µM
Hemolytic
Hemolytic_activity: [Ref.16871429] HC50>400 µM against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Biotechnol Lett. 2006 Sep 28(18):1431-7.