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Peptide record

TPDB12639

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12639
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
ILPWKWEWWPWRR
Physicochemical Analysis
C100H131N25O16
ANDCQGHMFSTYV
W
1939.30
11.32
3
1
7
+2
-4.59
-1.215
60.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
27500
1418.04
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
2
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 2 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
13
C100H131N25O16
1939.30
11.32
+2
-4.59
-1.215
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
21.7±8.16 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 21.7±8.16 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis