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Peptide record

TPDB12616

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12616
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FLGALWNPAKSVF
Physicochemical Analysis
C72H104N16O16
RDCEQHIMTY
ALF
1449.72
10.10
1
0
8
+1
-3.50
0.762
97.69
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
379.38
2
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
2
L
1
K
0
M
2
F
1
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 1 M: 0 F: 2 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C72H104N16O16
1449.72
10.10
+1
-3.50
0.762
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
>100 µM
Hemolytic Cytotoxic
0% Hemolysis | >100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Repurposing the scorpion venom peptide VmCT1 into an active peptide against Gram-negative ESKAPE pathogens. | Bioorg Chem | 2019
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
0 %
Hemolytic
Hemolytic_activity: [Ref.31212183] 0% hemolysis at 100 µmol/L for human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Bioorg Chem. 2019 Jun 8 90:103038. doi: 10.1016/j.bioorg.2019.103038.