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Peptide record

TPDB12609

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12609
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
IAPWKWPWWPWRR
Physicochemical Analysis
C97H125N25O14
NDCEQGHLMFSTYV
W
1865.22
12.41
3
0
7
+3
-5.77
-1.223
37.69
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
27500
1474.36
0
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
1
K
0
M
0
F
3
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 1 M: 0 F: 0 P: 3 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
13
C97H125N25O14
1865.22
12.41
+3
-5.77
-1.223
Evidence Records 2 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
15.6 µM
Hemolytic Cytotoxic
100% Hemolysis | 15.6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-function relationships in the tryptophan-rich, antimicrobial peptide indolicidin. | J Pept Sci | 2001
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis