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Peptide record

TPDB12604

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12604
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
NLVGSLLGGILKK
Physicochemical Analysis
C60H110N16O16
ARDCEQHMFPTWY
L
1311.63
10.60
2
0
6
+2
0.08
0.815
172.31
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
4
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 4 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C60H110N16O16
1311.63
10.60
+2
0.08
0.815
Evidence Records 3 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
180 µM
Hemolytic Cytotoxic
<5% Hemolysis | 180 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Somuncurins: Bioactive Peptides From the Skin of the Endangered Endemic Patagonian Frog Pleurodema somuncurense. | J Nat Prod | 2020
Evidence 2 Activity

Activity

6% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
6% Hemolysis | 400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Somuncurins: Bioactive Peptides From the Skin of the Endangered Endemic Patagonian Frog Pleurodema somuncurense. | J Nat Prod | 2020
Evidence 3 Activity

Activity

0% Cytotoxicity
Toxicity
100 µM
Cytotoxic
0% Cytotoxicity | 100 | µM | target cell: Human monocyte-derived macrophages

Target

Human monocyte-derived macrophages

Source & Reference

NA
DBAASP
Somuncurins: Bioactive Peptides From the Skin of the Endangered Endemic Patagonian Frog Pleurodema somuncurense. | J Nat Prod | 2020