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Peptide record

TPDB12601

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB12601
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RLIRRKRRIIRWL
Physicochemical Analysis
C83H151N33O14
ANDCEQGHMFPSTYV
R
1835.32
13.10
7
0
6
+7
1.95
-0.823
150.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
299.67
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
2
L
1
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 2 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C83H151N33O14
1835.32
13.10
+7
1.95
-0.823
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>128 µM
Hemolytic Cytotoxic
5% Hemolysis | >128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel design of short antimicrobial peptides derived from the bactericidal domain of avian ?-defensin-4. | Protein Pept Lett | 2012