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Peptide record

TPDB12566

Antibacterial Anticancer Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB12566
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RLRRIWWIRVRR
Physicochemical Analysis
C81H136N32O13
ANDCEQGHKMFPSTY
R
1766.18
13.10
6
0
6
+6
0.05
-0.983
121.67
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
622.81
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 1
Chemical Descriptors
12
C81H136N32O13
1766.18
13.10
+6
0.05
-0.983
Evidence Records 1 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
400 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 400 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Linear bactenecin analogs with cell selectivity and anti-endotoxic activity. | J Pept Sci | 2012