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Peptide record

TPDB12561

Antibacterial Anticancer Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB12561
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RWKIFKKVVKKW
Physicochemical Analysis
C83H132N22O13
ANDCEQGHLMPSTY
K
1646.10
11.85
6
0
6
+6
0.76
-0.842
80.83
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
668.25
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
5
K
0
M
1
F
0
P
0
S
0
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 2
Chemical Descriptors
12
C83H132N22O13
1646.10
11.85
+6
0.76
-0.842
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Killing
Toxicity
50 µM
Cytotoxic
0% Killing | 50 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Development of a novel short 12-meric papiliocin-derived peptide that is effective against Gram-negative sepsis. | Sci Rep | 2019
Evidence 2 Activity

Activity

0% Killing
Toxicity
50 µM
Cytotoxic
0% Killing | 50 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Development of a novel short 12-meric papiliocin-derived peptide that is effective against Gram-negative sepsis. | Sci Rep | 2019
Evidence 3 Activity

Activity

10% hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
10% hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Development of a novel short 12-meric papiliocin-derived peptide that is effective against Gram-negative sepsis. | Sci Rep | 2019