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Peptide record

TPDB12555

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB12555
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RWRRIVVIRVRR
Physicochemical Analysis
C74H133N31O13
ANDCEQGHLKMFPSTY
R
1665.07
13.10
6
0
6
+6
2.60
-0.525
137.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
330.32
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
12
C74H133N31O13
1665.07
13.10
+6
2.60
-0.525
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>256 µM
Hemolytic Cytotoxic
5% Hemolysis | >256 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of the Bioactivity and Mechanism of Bactenecin Derivatives Against Food-Pathogens. | Front Microbiol | 2019
Evidence 2 Activity

Activity

20% Killing
Toxicity
128 µM
Cytotoxic
20% Killing | 128 | µM | target cell: Human umbilical vein cells EA.hy926

Target

Human umbilical vein cells EA.hy926

Source & Reference

NA
DBAASP
Characterization of the Bioactivity and Mechanism of Bactenecin Derivatives Against Food-Pathogens. | Front Microbiol | 2019