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Peptide record

TPDB12545

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB12545
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
WFRVYRGIYRRR
Physicochemical Analysis
C81H122N28O15
ANDCEQHLKMPST
R
1728.04
12.23
5
0
6
+5
-1.04
-1.242
56.67
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
8480
490.73
2
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 1
Chemical Descriptors
12
C81H122N28O15
1728.04
12.23
+5
-1.04
-1.242
Evidence Records 1 records
Evidence 1 Activity

Activity

<1% Hemolysis
Toxicity
580 µM
Hemolytic Cytotoxic
<1% Hemolysis | 580 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Modified Cysteine-Deleted Tachyplesin (CDT) Analogs as Linear Antimicrobial Peptides: Influence of Chain Length, Positive Charge, and Hydrophobicity on Antimicrobial and Hemolytic Activity | Int J Pept Res Ther | 2014