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Peptide record

TPDB12523

WWSP (CN-2) Antibacterial Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB12523
WWSP (CN-2)
Antibacterial Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
AntiBP3 dbAMP DRAMP Peptipedia CPPsite3.0 MLCPP 2.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Cell-penetrating Peptides) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
PLILLRLLRGQF-NH2
Physicochemical Analysis
C69H119N19O14
ANDCEHKMSTWYV
L
1438.82
12.40
2
0
7
+2
-1.58
0.983
195.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
1
I
5
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 5 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C69H119N19O14
1438.82
12.40
+2
-1.58
0.983
Amidation
L
Amphipathic
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)/N=C/C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hek293, HeLa And CHO Cell Gram-Negative Strains (Escherichia Coli, Pseudomonas Aeruginosa) And Gram-Positive Strains (Staphylococcus Aureus, Enterococcus Faecalis).

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Highest uptake efficiency in CHO cells
In vitro
CCTTSSCCCCC
Additional Detail Fields 1 fields
CCTTSSCCCCC