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Peptide record

TPDB12517

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB12517
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
FLPKWALKWAAK
Physicochemical Analysis
C75H111N17O13
RNDCEQGHIMSTYV
AK
1458.81
10.84
3
0
8
+3
-3.04
0.058
90.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
754.04
0
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
3
K
0
M
1
F
1
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 3 M: 0 F: 1 P: 1 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
12
C75H111N17O13
1458.81
10.84
+3
-3.04
0.058
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
328.3 µM
Hemolytic Cytotoxic
50% Hemolysis | 328.3 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from The Skin Secretion of Odorrana schmackeri. | Toxins (Basel) | 2020
Evidence 2 Activity

Activity

55% Killing
Toxicity
0.1 µM
Cytotoxic
55% Killing | 0.1 | µM | target cell: Human microvascular endothelial cells HMEC-1

Target

Human microvascular endothelial cells HMEC-1

Source & Reference

NA
DBAASP
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from The Skin Secretion of Odorrana schmackeri. | Toxins (Basel) | 2020