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Peptide record

TPDB12512

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB12512
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KTVGKLALKHWL
Physicochemical Analysis
C67H112N18O14
RNDCEQIMFPSY
LK
1393.74
10.84
4
0
6
+3
0.45
0.042
130.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
394.62
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
3
L
3
K
0
M
0
F
0
P
0
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 3 K: 3 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
12
C67H112N18O14
1393.74
10.84
+3
0.45
0.042
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Killing
Toxicity
15 µM
Cytotoxic
5% Killing | 15 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Characterization and Antimicrobial Activity of Amphiphilic Peptide AP3 and Derivative Sequences. | Antibiotics (Basel) | 2019