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Peptide record

TPDB12493

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB12493
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
FWRRWQWRRRWF
Physicochemical Analysis
C97H128N32O14
ANDCEGHILKMPSTYV
R
1966.29
13.00
5
0
6
+5
-5.03
-2.000
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
22000
1118.86
1
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
0
K
0
M
2
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
12
C97H128N32O14
1966.29
13.00
+5
-5.03
-2.000
Evidence Records 3 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
8 µM
Hemolytic Cytotoxic
5% Hemolysis | 8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial Activity and Mechanism of Action of Bovine Lactoferricin Derivatives With Symmetrical Amino Acid Sequences. | Int J Mol Sci | 2018
Evidence 2 Activity

Activity

52.91% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
52.91% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial Activity and Mechanism of Action of Bovine Lactoferricin Derivatives With Symmetrical Amino Acid Sequences. | Int J Mol Sci | 2018
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Antibacterial Activity and Mechanism of Action of Bovine Lactoferricin Derivatives With Symmetrical Amino Acid Sequences. | Int J Mol Sci | 2018