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Peptide record

TPDB12480

Antibacterial Anticancer Antifungal Cell-penetrating Peptides Hemolysis Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB12480
Antibacterial Anticancer Antifungal Cell-penetrating Peptides Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CancerPPD 2.0 CAFPdb dbAMP CPPsite3.0 PD_Hemolysis
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
IFGTILGFLKGL
Physicochemical Analysis
C64H103N13O14
ARNDCEQHMPSWYV
GL
1278.60
10.10
1
0
7
+1
-3.40
1.683
162.50
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
2
I
3
L
1
K
0
M
2
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 3 K: 1 M: 0 F: 2 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C64H103N13O14
1278.60
10.10
+1
-3.40
1.683
Evidence Records 5 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>64 µM
Hemolytic Cytotoxic
50% Hemolysis | >64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial and Anticancer Properties of Synthetic Peptides Derived from the Wasp Parachartergus fraternus. | Chembiochem | 2020
Evidence 2 Activity

Activity

50% Cell death
Toxicity
20.2±1.9 µM
Cytotoxic
50% Cell death | 20.2±1.9 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Antimicrobial and Anticancer Properties of Synthetic Peptides Derived from the Wasp Parachartergus fraternus. | Chembiochem | 2020
Evidence 3 Activity

Activity

50% Cell death
Toxicity
18.9±1.1 µM
Cytotoxic
50% Cell death | 18.9±1.1 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Antimicrobial and Anticancer Properties of Synthetic Peptides Derived from the Wasp Parachartergus fraternus. | Chembiochem | 2020
Evidence 4 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Chembiochem. 2021 Apr 16 22(8):1415-1424.
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis