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Peptide record

TPDB12450

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB12450
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KKWRKWLAKKWW
Physicochemical Analysis
C89H130N24O13
NDCEQGHIMFPSTYV
K
1744.16
11.85
6
0
6
+6
-2.37
-1.833
40.83
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
22000
1261.35
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
5
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
12
C89H130N24O13
1744.16
11.85
+6
-2.37
-1.833
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
25 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 25 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Boosting salt resistance of short antimicrobial peptides. | Antimicrob Agents Chemother | 2013