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Peptide record

TPDB12425

Antibacterial Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB12425
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
QQCRRPLYCRRR
Physicochemical Analysis
C66H115N29O16S2
ANDEGHIKMFSTWV
R
1634.94
11.81
5
0
2
+5
3.68
-1.967
32.50
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
1615
98.78
5
Residue Composition
number
0
A
5
R
0
N
0
D
2
C
0
E
2
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 2 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
12
C66H115N29O16S2
1634.94
11.81
+5
3.68
-1.967
Evidence Records 1 records
Evidence 1 Activity

Activity

0.88% Hemolysis
Toxicity
25-100 µM
Hemolytic Cytotoxic
0.88% Hemolysis | 25-100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent Chimeric Antimicrobial Derivatives of the Medicago truncatula NCR247 Symbiotic Peptide. | Front Microbiol | 2020