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Peptide record

TPDB12404

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB12404
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWLRRPWRWWR
Physicochemical Analysis
C85H120N28O12
ANDCEQGHIMFSTYV
RW
1726.07
12.88
5
0
5
+5
-3.28
-2.118
35.45
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
22000
1274.57
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
1
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
11
C85H120N28O12
1726.07
12.88
+5
-3.28
-2.118
Evidence Records 1 records
Evidence 1 Activity

Activity

55.6% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
55.6% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design, Synthesis, and Antimicrobial Activities of Novel Functional Peptides Against Gram-positive and Gram-negative Bacteria. | Chem Biol Drug Des | 2019