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Peptide record

TPDB12398

Antibacterial Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB12398
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
FLPGILKVAAK
Physicochemical Analysis
C57H97N13O12
RNDCEQHMSTWY
ALK
1156.48
10.60
2
0
7
+2
-0.39
1.173
150.91
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
2
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 2 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
11
C57H97N13O12
1156.48
10.60
+2
-0.39
1.173
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
381.4 µM
Hemolytic Cytotoxic
50% Hemolysis | 381.4 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from The Skin Secretion of Odorrana schmackeri. | Toxins (Basel) | 2020
Evidence 2 Activity

Activity

45% Killing
Toxicity
0.1 µM
Cytotoxic
45% Killing | 0.1 | µM | target cell: Human microvascular endothelial cells HMEC-1

Target

Human microvascular endothelial cells HMEC-1

Source & Reference

NA
DBAASP
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from The Skin Secretion of Odorrana schmackeri. | Toxins (Basel) | 2020