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Peptide record

TPDB12396

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB12396
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia ToxinPred 3.0
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and ToxinPred 3.0, with an available 3D structural model.
Sequence
FILKRSYPQYY
Physicochemical Analysis
C73H104N16O17
ANDCEGHMTWV
Y
1477.73
9.89
2
0
6
+2
-1.86
-0.645
70.91
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
4470
302.49
5
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
1
L
1
K
0
M
1
F
1
P
1
S
0
T
0
W
3
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 3 V: 0
Chemical Descriptors
11
C73H104N16O17
1477.73
9.89
+2
-1.86
-0.645
Evidence Records 2 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
400 µM
Hemolytic Cytotoxic
<5% Hemolysis | 400 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Somuncurins: Bioactive Peptides From the Skin of the Endangered Endemic Patagonian Frog Pleurodema somuncurense. | J Nat Prod | 2020
Evidence 2 Activity

Activity

0% Cytotoxicity
Toxicity
100 µM
Cytotoxic
0% Cytotoxicity | 100 | µM | target cell: Human monocyte-derived macrophages

Target

Human monocyte-derived macrophages

Source & Reference

NA
DBAASP
Somuncurins: Bioactive Peptides From the Skin of the Endangered Endemic Patagonian Frog Pleurodema somuncurense. | J Nat Prod | 2020