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Peptide record

TPDB12386

Antibacterial Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB12386
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 11-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWFRVYRGIYR
Physicochemical Analysis
C75H110N22O14
ANDCEQHLMPST
R
1543.84
11.35
4
0
6
+4
-1.67
-0.891
61.82
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
8480
549.28
2
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 2 V: 1
Chemical Descriptors
11
C75H110N22O14
1543.84
11.35
+4
-1.67
-0.891
Evidence Records 2 records
Evidence 1 Activity

Activity

<1% Hemolysis
Toxicity
650 µM
Hemolytic Cytotoxic
<1% Hemolysis | 650 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Modified Cysteine-Deleted Tachyplesin (CDT) Analogs as Linear Antimicrobial Peptides: Influence of Chain Length, Positive Charge, and Hydrophobicity on Antimicrobial and Hemolytic Activity | Int J Pept Res Ther | 2014
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
500 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 500 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Modified Cysteine-Deleted Tachyplesin (CDT) Analogs as Linear Antimicrobial Peptides: Influence of Chain Length, Positive Charge, and Hydrophobicity on Antimicrobial and Hemolytic Activity | Int J Pept Res Ther | 2014