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Peptide record

TPDB12370

Antibacterial Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB12370
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
RLIVKVRIWRR
Physicochemical Analysis
C69H123N25O12
ANDCEQGHMFPSTY
R
1494.90
12.88
5
0
6
+5
1.34
-0.145
159.09
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
367.92
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
11
C69H123N25O12
1494.90
12.88
+5
1.34
-0.145
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Cytotoxicity
Toxicity
10 µM
Cytotoxic
0% Cytotoxicity | 10 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
A Safe and Multitasking Antimicrobial Decapeptide: The Road from De Novo Design to Structural and Functional Characterization. | Int J Mol Sci | 2020
Evidence 2 Activity

Activity

0% Cytotoxicity
Toxicity
10 µM
Cytotoxic
0% Cytotoxicity | 10 | µM | target cell: Human fibroblasts WI-38

Target

Human fibroblasts WI-38

Source & Reference

NA
DBAASP
A Safe and Multitasking Antimicrobial Decapeptide: The Road from De Novo Design to Structural and Functional Characterization. | Int J Mol Sci | 2020
Evidence 3 Activity

Activity

0% Cytotoxicity
Toxicity
10 µM
Cytotoxic
0% Cytotoxicity | 10 | µM | target cell: Human lung fibroblasts TIG-3

Target

Human lung fibroblasts TIG-3

Source & Reference

NA
DBAASP
A Safe and Multitasking Antimicrobial Decapeptide: The Road from De Novo Design to Structural and Functional Characterization. | Int J Mol Sci | 2020