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Peptide record

TPDB12348

Antibacterial Cell-penetrating Peptides Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB12348
Antibacterial Cell-penetrating Peptides Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
AntiBP3 Peptipedia CPPsite3.0
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Cell-penetrating Peptides, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and CPPsite3.0, with an available 3D structural model.
Sequence
KCRRWQWRMKK
Physicochemical Analysis
C71H116N26O13S2
ANDEGHILFPSTYV
RK
1605.99
12.14
6
0
3
+6
1.81
-2.373
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
684.94
2
Residue Composition
number
0
A
3
R
0
N
0
D
1
C
0
E
1
Q
0
G
0
H
0
I
0
L
3
K
1
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 3 M: 1 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
11
C71H116N26O13S2
1605.99
12.14
+6
1.81
-2.373
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>256 µM
Hemolytic Cytotoxic
5% Hemolysis | >256 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antibacterial Activity and Mechanism of Action of Bovine Lactoferricin Derivatives With Symmetrical Amino Acid Sequences. | Int J Mol Sci | 2018
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Antibacterial Activity and Mechanism of Action of Bovine Lactoferricin Derivatives With Symmetrical Amino Acid Sequences. | Int J Mol Sci | 2018