Back to search

Peptide record

TPDB12343

Antibacterial Antifungal Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB12343
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
HTLCMDGGATY
Physicochemical Analysis
C48H73N13O17S2
RNEQIKFPSWV
GT
1168.30
4.94
1
1
4
-1
0.35
-0.018
44.55
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
1490
127.54
4
Residue Composition
number
1
A
0
R
0
N
1
D
1
C
0
E
0
Q
2
G
1
H
0
I
1
L
0
K
1
M
0
F
0
P
0
S
2
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 1 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 1 K: 0 M: 1 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 1 V: 0
Chemical Descriptors
11
C48H73N13O17S2
1168.30
4.94
-1
0.35
-0.018
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20 µM

Target

Streptococcus pyogenes

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active specifically against S. pyogenes (MIC 20 uM). UPdated 7/2021
Evidence 2 Activity

Activity

MIC
Antifungal
20 µM

Target

Streptococcus pyogenes

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active specifically against S. pyogenes (MIC 20 uM). UPdated 7/2021
Evidence 3 Activity

Activity

8% Killing
Toxicity
500 µM
Cytotoxic
8% Killing | 500 | µM | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
M-Brucin, an antibacterial peptide against Staphylococcus epidermidis and Streptococcus pyogenes | J Appl Pharm Sci | 2018