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Peptide record

TPDB12341

Antibacterial Antifungal Hemolysis Toxicity standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB12341
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP PD_Hemolysis
standard
No
A 11-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
FLKWALKWAAK
Physicochemical Analysis
C70H104N16O12
RNDCEQGHIMPSTYV
AK
1361.70
10.84
3
0
8
+3
-3.49
0.209
98.18
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
807.82
0
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
2
L
3
K
0
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
11
C70H104N16O12
1361.70
10.84
+3
-3.49
0.209
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
64.03 µM
Hemolytic Cytotoxic
50% Hemolysis | 64.03 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from The Skin Secretion of Odorrana schmackeri. | Toxins (Basel) | 2020
Evidence 2 Activity

Activity

30% Killing
Toxicity
0.1 µM
Cytotoxic
30% Killing | 0.1 | µM | target cell: Human microvascular endothelial cells HMEC-1

Target

Human microvascular endothelial cells HMEC-1

Source & Reference

NA
DBAASP
Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinin-1 Peptide from The Skin Secretion of Odorrana schmackeri. | Toxins (Basel) | 2020
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis