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Peptide record

TPDB12295

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB12295
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
QAKIRVRLSA
Physicochemical Analysis
C49H92N18O13
NDCEGHMFPTWY
AR
1141.38
12.41
3
0
5
+3
2.18
-0.110
127.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C49H92N18O13
1141.38
12.41
+3
2.18
-0.110
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
16-128 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

active against E. coli (MIC 16-128 ug/ml), P. aeruginosa ATCC 27853 or 885149 or 891 (MIC 32-64 ug/ml), K. pneumoniae W99FI0057 (MI
Evidence 2 Activity

Activity

MIC
Antibacterial
32-64 µg/mL

Target

Pseudomonas aeruginosa ATCC 27853 or 885149 or 891

Source & Reference

NA

Other

active against E. coli (MIC 16-128 ug/ml), P. aeruginosa ATCC 27853 or 885149 or 891 (MIC 32-64 ug/ml), K. pneumoniae W99FI0057 (MIC 64 ug/ml), S. aureus ATCC 25923 or MIU-68A (MIC 64->128 ug/
Evidence 3 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Klebsiella pneumoniae W99FI0057

Source & Reference

NA

Other

E. coli (MIC 16-128 ug/ml), P. aeruginosa ATCC 27853 or 885149 or 891 (MIC 32-64 ug/ml), K. pneumoniae W99FI0057 (MIC 64 ug/ml), S. aureus ATCC 25923 or MIU-68A (MIC 64->128 ug/ml). mainly acttive against Gram- bacter
Evidence 4 Activity

Activity

MIC
Antibacterial
64->128 µg/mL

Target

Staphylococcus aureus ATCC 25923 or MIU-68A

Source & Reference

NA

Other

sa ATCC 27853 or 885149 or 891 (MIC 32-64 ug/ml), K. pneumoniae W99FI0057 (MIC 64 ug/ml), S. aureus ATCC 25923 or MIU-68A (MIC 64->128 ug/ml). mainly acttive against Gram- bacteria.