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Peptide record

TPDB12281

Antibacterial Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB12281
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
QKRPRVRLSA
Physicochemical Analysis
C51H95N21O13
NDCEGHIMFTWY
R
1210.45
12.71
4
0
3
+4
3.92
-1.350
78.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C51H95N21O13
1210.45
12.71
+4
3.92
-1.350
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>128 µM
Hemolytic Cytotoxic
5% Hemolysis | >128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Multiple Strategy Optimization of Specifically Targeted Antimicrobial Peptide Based on Structure - Activity Relationships to Enhance Bactericidal Efficiency. | ACS Biomater Sci Eng | 2020