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Peptide record

TPDB12268

Antibacterial standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB12268
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 9-aa standard-residue antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GWWRRTVRK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C57H89N21O11
ANDCEQHILMFPSY
R
1244.47
12.71
4
0
3
+4
4.80
-1.789
32.22
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
8.84
1
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
1
T
2
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 2 Y: 0 V: 1
Chemical Descriptors
9 reviewed residue count
C57H89N21O11 sequence-only estimate (linear, free termini)
1244.47 sequence-only estimate (linear, free termini)
12.71 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
4.80 sequence-only estimate (linear, free termini)
-1.789 sequence-only estimate (linear, free termini)
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
3.1 µM

Target

C. glutamicum ATCC 13032

Source & Reference

NA

Other

Active against C. glutamicum ATCC 13032 (MIC 3.1 uM), S.aureus ATCC 9144 (MIC 100 uM), P. aeruginosa ATCC 27853 (MIC 25 uM), and E. coli ATCC
Evidence 2 Activity

Activity

MIC
Antibacterial
100 µM

Target

S.aureus ATCC 9144

Source & Reference

NA

Other

Active against C. glutamicum ATCC 13032 (MIC 3.1 uM), S.aureus ATCC 9144 (MIC 100 uM), P. aeruginosa ATCC 27853 (MIC 25 uM), and E. coli ATCC 25922 (MIC 50 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
25 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

NA

Other

Active against C. glutamicum ATCC 13032 (MIC 3.1 uM), S.aureus ATCC 9144 (MIC 100 uM), P. aeruginosa ATCC 27853 (MIC 25 uM), and E. coli ATCC 25922 (MIC 50 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
50 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

(MIC 3.1 uM), S.aureus ATCC 9144 (MIC 100 uM), P. aeruginosa ATCC 27853 (MIC 25 uM), and E. coli ATCC 25922 (MIC 50 uM).