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Peptide record

TPDB12252

Antibacterial Anticancer Antifungal Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB12252
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
RWRFKWWKK
Physicochemical Analysis
C72H101N21O10
ANDCEQGHILMPSTYV
KW
1420.73
12.43
5
0
4
+5
-2.09
-2.289
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
1161.38
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
1
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
9
C72H101N21O10
1420.73
12.43
+5
-2.09
-2.289
Evidence Records 2 records
Evidence 1 Activity

Activity

3% Hemolysis
Toxicity
320 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 320 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A designed antifungal peptide with therapeutic potential for clinical drug-resistant Candida albicans. | Biochem Biophys Res Commun | 2020
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Rat myoblast L6 cells

Target

Rat myoblast L6 cells

Source & Reference

NA
DBAASP
A designed antifungal peptide with therapeutic potential for clinical drug-resistant Candida albicans. | Biochem Biophys Res Commun | 2020