Back to search

Peptide record

TPDB12245

Antibacterial Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB12245
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 8-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWYKKWYK
Physicochemical Analysis
C64H88N14O11
ARNDCEQGHILMFPSTV
K
1229.49
10.41
4
0
4
+4
-1.62
-2.500
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
13980
1137.06
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
2
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 2 V: 0
Chemical Descriptors
8
C64H88N14O11
1229.49
10.41
+4
-1.62
-2.500
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
418 µM
Cytotoxic
50% Cytotoxicity | 418 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Cell-selectivity of tryptophan and tyrosine in amphiphilic ?-helical antimicrobial peptides against drug-resistant bacteria. | Biochem Biophys Res Commun | 2018
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Cell-selectivity of tryptophan and tyrosine in amphiphilic ?-helical antimicrobial peptides against drug-resistant bacteria. | Biochem Biophys Res Commun | 2018