Back to search

Peptide record

TPDB12227

Antibacterial Toxicity standard
8 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB12227
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 8-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
LYKAIRRK
Physicochemical Analysis
C48H86N16O10
NDCEQGHMFPSTWV
RK
1047.31
11.51
4
0
4
+4
1.62
-1.000
110.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
142.27
1
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
8
C48H86N16O10
1047.31
11.51
+4
1.62
-1.000
Evidence Records 2 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
256 µM
Hemolytic Cytotoxic
<5% Hemolysis | 256 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The Central Hinge Link Truncation of the Antimicrobial Peptide Fowlicidin-3 Enhances Its Cell Selectivity without Antibacterial Activity Loss. | Antimicrob Agents Chemother | 2016
Evidence 2 Activity

Activity

<40% Killing
Toxicity
256 µM
Cytotoxic
<40% Killing | 256 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
The Central Hinge Link Truncation of the Antimicrobial Peptide Fowlicidin-3 Enhances Its Cell Selectivity without Antibacterial Activity Loss. | Antimicrob Agents Chemother | 2016