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Peptide record

TPDB12219

Antibacterial Antifungal standard
50 amino acids
Basic Information
3D PDB MODEL
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TPDB12219
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 50-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
LPLSINPWRPPFPGRPLPGGPLVLPGCVCVRAPCYCSPSRQKDFPGFEHY
Physicochemical Analysis
C255H382N68O62S4
MT
P
5520.50
8.70
6
2
16
+3
4.13
-0.198
66.20
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
8730
158.14
11
Residue Composition
number
1
A
4
R
1
N
1
D
4
C
1
E
1
Q
5
G
1
H
1
I
5
L
1
K
0
M
3
F
12
P
3
S
0
T
1
W
2
Y
3
V
Amino Acid Distribution
A: 1 R: 4 N: 1 D: 1 C: 4 E: 1 Q: 1 G: 5 H: 1 I: 1 L: 5 K: 1 M: 0 F: 3 P: 12 S: 3 T: 0 W: 1 Y: 2 V: 3
Chemical Descriptors
50
C255H382N68O62S4
5520.50
8.70
+3
4.13
-0.198
Evidence Records 10 records
Evidence 1 Activity

Activity

MIC
Antibacterial
25 µM

Target

M. luteus SDMCC210058

Source & Reference

NA

Other

Active against Gram+ S. aureus AS1.89 (MIC 25 uM), M. luteus SDMCC210058 (MIC 25 uM), B. subtilis ATCC9372 (MIC 50 uM), Gram- A. hydrohila (MIC 25 uM), E. coli DH5alpha (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
50 µM

Target

B. subtilis ATCC9372

Source & Reference

NA

Other

Active against Gram+ S. aureus AS1.89 (MIC 25 uM), M. luteus SDMCC210058 (MIC 25 uM), B. subtilis ATCC9372 (MIC 50 uM), Gram- A. hydrohila (MIC 25 uM), E. coli DH5alpha (MIC 12.5 uM), and V. anguillarum SDMCC
Evidence 3 Activity

Activity

MIC
Antibacterial
25 µM

Target

A. hydrohila

Source & Reference

NA

Other

9 (MIC 25 uM), M. luteus SDMCC210058 (MIC 25 uM), B. subtilis ATCC9372 (MIC 50 uM), Gram- A. hydrohila (MIC 25 uM), E. coli DH5alpha (MIC 12.5 uM), and V. anguillarum SDMCC210204 (MIC 12.5 uM). The N-term
Evidence 4 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Escherichia coli DH5alpha

Source & Reference

NA

Other

DMCC210058 (MIC 25 uM), B. subtilis ATCC9372 (MIC 50 uM), Gram- A. hydrohila (MIC 25 uM), E. coli DH5alpha (MIC 12.5 uM), and V. anguillarum SDMCC210204 (MIC 12.5 uM). The N-terminal Pro-rich domain is proposed
Evidence 5 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

V. anguillarum SDMCC210204

Source & Reference

NA

Other

ATCC9372 (MIC 50 uM), Gram- A. hydrohila (MIC 25 uM), E. coli DH5alpha (MIC 12.5 uM), and V. anguillarum SDMCC210204 (MIC 12.5 uM). The N-terminal Pro-rich domain is proposed to be essential for activity. Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
25 µM

Target

M. luteus SDMCC210058

Source & Reference

Antifungipept

Other

Active against Gram+ S. aureus AS1.89 (MIC 25 uM), M. luteus SDMCC210058 (MIC 25 uM), B. subtilis ATCC9372 (MIC 50 uM), Gram- A. hydrohila (MIC 25 uM), E. coli DH5alpha (MIC
Evidence 7 Activity

Activity

MIC
Antifungal
50 µM

Target

B. subtilis ATCC9372

Source & Reference

Antifungipept

Other

Active against Gram+ S. aureus AS1.89 (MIC 25 uM), M. luteus SDMCC210058 (MIC 25 uM), B. subtilis ATCC9372 (MIC 50 uM), Gram- A. hydrohila (MIC 25 uM), E. coli DH5alpha (MIC 12.5 uM), and V. anguillarum SDMCC
Evidence 8 Activity

Activity

MIC
Antifungal
25 µM

Target

A. hydrohila

Source & Reference

Antifungipept

Other

9 (MIC 25 uM), M. luteus SDMCC210058 (MIC 25 uM), B. subtilis ATCC9372 (MIC 50 uM), Gram- A. hydrohila (MIC 25 uM), E. coli DH5alpha (MIC 12.5 uM), and V. anguillarum SDMCC210204 (MIC 12.5 uM). The N-term
Evidence 9 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Escherichia coli DH5alpha

Source & Reference

Antifungipept

Other

DMCC210058 (MIC 25 uM), B. subtilis ATCC9372 (MIC 50 uM), Gram- A. hydrohila (MIC 25 uM), E. coli DH5alpha (MIC 12.5 uM), and V. anguillarum SDMCC210204 (MIC 12.5 uM). The N-terminal Pro-rich domain is proposed
Evidence 10 Activity

Activity

MIC
Antifungal
12.5 µM

Target

V. anguillarum SDMCC210204

Source & Reference

Antifungipept

Other

ATCC9372 (MIC 50 uM), Gram- A. hydrohila (MIC 25 uM), E. coli DH5alpha (MIC 12.5 uM), and V. anguillarum SDMCC210204 (MIC 12.5 uM). The N-terminal Pro-rich domain is proposed to be essential for activity. Updated 7/2021