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Peptide record

TPDB12213

Antibacterial Anticancer Antifungal Antiparasitic standard
50 amino acids
Basic Information
3D PDB MODEL
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TPDB12213
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia dbACP AFP-GFuse Antifungipept CAFPdb
standard
No
A 50-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
YRGGYTGPIPRPPPIGRPPFRPVCNACYRLSVSDARNCCIKFGSCCHLVK
Physicochemical Analysis
C243H382N74O62S6
EQMW
P
5524.52
9.56
9
1
15
+7
5.35
-0.248
60.40
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
4845
87.70
15
Residue Composition
number
2
A
6
R
2
N
1
D
6
C
0
E
0
Q
5
G
1
H
3
I
2
L
2
K
0
M
2
F
8
P
3
S
1
T
0
W
3
Y
3
V
Amino Acid Distribution
A: 2 R: 6 N: 2 D: 1 C: 6 E: 0 Q: 0 G: 5 H: 1 I: 3 L: 2 K: 2 M: 0 F: 2 P: 8 S: 3 T: 1 W: 0 Y: 3 V: 3
Chemical Descriptors
50
C243H382N74O62S6
5524.52
9.56
+7
5.35
-0.248
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.5-5 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against M. luteus (MIC 2.5-5 uM), E-coli 363 (MIC >40 uM), F. oxysporum (MIC 5-10 uM), S.cerevisiae TGY (MIC >100 uM). War
Evidence 2 Activity

Activity

MIC
Antibacterial
5-10 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP

Other

active against M. luteus (MIC 2.5-5 uM), E-coli 363 (MIC >40 uM), F. oxysporum (MIC 5-10 uM), S.cerevisiae TGY (MIC >100 uM). Warning: nonstandard assays against bacteria in 1% bacto
Evidence 3 Activity

Activity

MIC
Antibacterial
>100 µM

Target

S.cerevisiae TGY

Source & Reference

dbAMP DRAMP

Other

ve against M. luteus (MIC 2.5-5 uM), E-coli 363 (MIC >40 uM), F. oxysporum (MIC 5-10 uM), S.cerevisiae TGY (MIC >100 uM). Warning: nonstandard assays against bacteria in 1% bactotryptone.
Evidence 4 Activity

Activity

MIC
Antifungal
2.5-5 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against M. luteus (MIC 2.5-5 uM), E-coli 363 (MIC >40 uM), F. oxysporum (MIC 5-10 uM), S.cerevisiae TGY (MIC >100 uM). War
Evidence 5 Activity

Activity

MIC
Antifungal
5-10 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

active against M. luteus (MIC 2.5-5 uM), E-coli 363 (MIC >40 uM), F. oxysporum (MIC 5-10 uM), S.cerevisiae TGY (MIC >100 uM). Warning: nonstandard assays against bacteria in 1% bacto
Evidence 6 Activity

Activity

MIC
Antifungal
>100 µM

Target

S.cerevisiae TGY

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ve against M. luteus (MIC 2.5-5 uM), E-coli 363 (MIC >40 uM), F. oxysporum (MIC 5-10 uM), S.cerevisiae TGY (MIC >100 uM). Warning: nonstandard assays against bacteria in 1% bactotryptone.
Evidence 7 Activity

Activity

MIC
Antiparasitic
2.5-5 µM

Target

M. luteus

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against M. luteus (MIC 2.5-5 uM), E-coli 363 (MIC >40 uM), F. oxysporum (MIC 5-10 uM), S.cerevisiae TGY (MIC >100 uM). War
Evidence 8 Activity

Activity

MIC
Antiparasitic
5-10 µM

Target

F. oxysporum

Source & Reference

DRAMP

Other

active against M. luteus (MIC 2.5-5 uM), E-coli 363 (MIC >40 uM), F. oxysporum (MIC 5-10 uM), S.cerevisiae TGY (MIC >100 uM). Warning: nonstandard assays against bacteria in 1% bacto
Evidence 9 Activity

Activity

MIC
Antiparasitic
>100 µM

Target

S.cerevisiae TGY

Source & Reference

DRAMP

Other

ve against M. luteus (MIC 2.5-5 uM), E-coli 363 (MIC >40 uM), F. oxysporum (MIC 5-10 uM), S.cerevisiae TGY (MIC >100 uM). Warning: nonstandard assays against bacteria in 1% bactotryptone.