Back to search

Peptide record

TPDB12210

Antibacterial Anticancer Antifungal Antiparasitic standard
49 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB12210
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF AFP-GFuse Antifungipept CAFPdb
standard
No
A 49-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
ACQCPDAISGWTHTDYQCHGLENKMYRHVYAICMNGTQVYCRTEWGSSC
Physicochemical Analysis
C238H351N69O74S8
F
C
5619.30
6.28
6
4
16
-1
5.10
-0.490
41.84
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
17335
308.49
22
Residue Composition
number
3
A
2
R
2
N
2
D
6
C
2
E
3
Q
4
G
3
H
2
I
1
L
1
K
2
M
0
F
1
P
3
S
4
T
2
W
4
Y
2
V
Amino Acid Distribution
A: 3 R: 2 N: 2 D: 2 C: 6 E: 2 Q: 3 G: 4 H: 3 I: 2 L: 1 K: 1 M: 2 F: 0 P: 1 S: 3 T: 4 W: 2 Y: 4 V: 2
Chemical Descriptors
49
C238H351N69O74S8
5619.30
6.28
-1
5.10
-0.490
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against B. subtilis (MIC ~2 uM), S. aureus (MIC ~2 uM), E. coli (MIC ~7 uM), V. cholerae, P. aeruginosa (MIC ~15 uM), and L. monocytogenes (MIC ~22 uM). Also, MRSA (MIC 6-12 uM), anti-VRE (MIC >16 uM), S-mutans strain DIGK119 (MIC >24 uM), G-parahaemolysans strain SKVG1 (MIC > 24 uM), and S-gordonii (MIC > 24 uM). Warning: other bacteria not tested.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against B. subtilis (MIC ~2 uM), S. aureus (MIC ~2 uM), E. coli (MIC ~7 uM), V. cholerae, P. aeruginosa (MIC ~15 uM), and L. monocytogenes (MIC ~22 uM). Also, MRSA (MIC 6-12 uM), anti-VRE (MIC >16 uM), S-mutans strain DIGK119 (MIC >24 uM), G-parahaemolysans strain SKVG1 (MIC > 24 uM), and S-gordonii (MIC > 24 uM). Warning: other bacteria not tested.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against B. subtilis (MIC ~2 uM), S. aureus (MIC ~2 uM), E. coli (MIC ~7 uM), V. cholerae, P. aeruginosa (MIC ~15 uM), and L. monocytogenes (MIC ~22 uM). Also, MRSA (MIC 6-12 uM), anti-VRE (MIC >16 uM), S-mutans strain DIGK119 (MIC >24 uM), G-parahaemolysans strain SKVG1 (MIC > 24 uM), and S-gordonii (MIC > 24 uM). Warning: other bacteria not tested.