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Peptide record

TPDB12207

Antibacterial Antiviral Hemolysis Toxicity standard
49 amino acids
Basic Information
3D PDB MODEL
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TPDB12207
Antibacterial Antiviral Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 49-aa standard natural multi-activity (Antibacterial, Antiviral, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
FKFGSFIKRMWRSKLAKKLRAKGKELLRDYANRVLSPEEEAAAPAPVPA
Physicochemical Analysis
C255H413N73O65S1
CQHT
A
5573.59
10.91
12
5
22
+7
12.18
-0.531
75.92
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
6990
125.41
5
Residue Composition
number
8
A
5
R
1
N
1
D
0
C
4
E
0
Q
2
G
0
H
1
I
5
L
7
K
1
M
3
F
4
P
3
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 8 R: 5 N: 1 D: 1 C: 0 E: 4 Q: 0 G: 2 H: 0 I: 1 L: 5 K: 7 M: 1 F: 3 P: 4 S: 3 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
49
C255H413N73O65S1
5573.59
10.91
+7
12.18
-0.531
Evidence Records 7 records
Evidence 1 Activity

Activity

30% Hemolysis
Toxicity
3.1 µM
Hemolytic Cytotoxic
30% Hemolysis | 3.1 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Meucin-49, a multifunctional scorpion venom peptide with bactericidal synergy with neurotoxins. | Amino Acids | 2018
Evidence 2 Activity

Activity

65% Hemolysis
Toxicity
6.3 µM
Hemolytic Cytotoxic
65% Hemolysis | 6.3 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Meucin-49, a multifunctional scorpion venom peptide with bactericidal synergy with neurotoxins. | Amino Acids | 2018
Evidence 3 Activity

Activity

90% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
90% Hemolysis | 12.5 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Meucin-49, a multifunctional scorpion venom peptide with bactericidal synergy with neurotoxins. | Amino Acids | 2018
Evidence 4 Activity

Activity

100% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
100% Hemolysis | 25 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Meucin-49, a multifunctional scorpion venom peptide with bactericidal synergy with neurotoxins. | Amino Acids | 2018
Evidence 5 Activity

Activity

100% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
100% Hemolysis | 25 | µM | target cell: Lizard erythrocytes

Target

Lizard erythrocytes

Source & Reference

NA
DBAASP
Meucin-49, a multifunctional scorpion venom peptide with bactericidal synergy with neurotoxins. | Amino Acids | 2018
Evidence 6 Activity

Activity

60% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
60% Hemolysis | 25 | µM | target cell: Bird erythrocytes

Target

Bird erythrocytes

Source & Reference

NA
DBAASP
Meucin-49, a multifunctional scorpion venom peptide with bactericidal synergy with neurotoxins. | Amino Acids | 2018
Evidence 7 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis