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Peptide record

TPDB12203

Antibacterial Antifungal Antiparasitic Toxicity standard
49 amino acids
Basic Information
3D PDB MODEL
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TPDB12203
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP dbAMP 3.0
standard
No
A 49-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
IFGLLLHGAIHVGKLIHGLVRRHGEEQLDDLEQLDKRALDYNPGRPGFD
Physicochemical Analysis
C248H392N74O70
CMSTW
L
5530.29
6.04
10
8
19
-2
14.45
-0.390
111.43
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1490
26.94
4
Residue Composition
number
2
A
4
R
1
N
5
D
0
C
3
E
2
Q
7
G
4
H
3
I
9
L
2
K
0
M
2
F
2
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 4 N: 1 D: 5 C: 0 E: 3 Q: 2 G: 7 H: 4 I: 3 L: 9 K: 2 M: 0 F: 2 P: 2 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
49
C248H392N74O70
5530.29
6.04
-2
14.45
-0.390
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 2 Activity

Activity

9.30±3.40% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
9.30±3.40% Hemolysis | 20 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017