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Peptide record

TPDB12198

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
48 amino acids
Basic Information
3D PDB MODEL
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TPDB12198
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 48-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RRSRRGRGGGRRGGSGGRGGRGGGGRSGAGSSIAGVGSRGGGGGRHYA
Physicochemical Analysis
C171H296N86O56
NDCEQLKMFPTW
G
4452.77
13.10
13
0
6
+12
10.00
-1.217
20.42
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
33.46
7
Residue Composition
number
3
A
12
R
0
N
0
D
0
C
0
E
0
Q
23
G
1
H
1
I
0
L
0
K
0
M
0
F
0
P
6
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 3 R: 12 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 23 H: 1 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 6 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
48
C171H296N86O56
4452.77
13.10
+12
10.00
-1.217
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Amphibian cathelicidin fills the evolutionary gap of cathelicidin in vertebrate. | Amino Acids | 2012
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human umbilical vein endothelial cells HUVEC

Target

Human umbilical vein endothelial cells HUVEC

Source & Reference

NA
DBAASP
Amphibian cathelicidin fills the evolutionary gap of cathelicidin in vertebrate. | Amino Acids | 2012
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.22009138]No cytotoxic against HUVEC or RMMCs at the concentration of 0.4 mg/ml.

Source & Reference

NA
DRAMP
Amino Acids. 2012 Aug 43(2):677-685.