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Peptide record

TPDB12185

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
48 amino acids
Basic Information
3D PDB MODEL
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TPDB12185
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb AI4AVP dbAMP 3.0
standard
No
A 48-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
IFGSIYHRKCVVKNRCETVSGHKTCKDLTCCRAVIFRHERPEVCRPQT
Physicochemical Analysis
C239H392N78O66S6
MW
RC
5606.58
9.26
13
4
13
+6
15.78
-0.463
64.79
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1865
33.26
15
Residue Composition
number
1
A
6
R
1
N
1
D
6
C
3
E
1
Q
2
G
3
H
3
I
1
L
4
K
0
M
2
F
2
P
2
S
4
T
0
W
1
Y
5
V
Amino Acid Distribution
A: 1 R: 6 N: 1 D: 1 C: 6 E: 3 Q: 1 G: 2 H: 3 I: 3 L: 1 K: 4 M: 0 F: 2 P: 2 S: 2 T: 4 W: 0 Y: 1 V: 5
Chemical Descriptors
48
C239H392N78O66S6
5606.58
9.26
+6
15.78
-0.463
Evidence Records 17 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

L. anguillarum serotype O2

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aur
Evidence 2 Activity

Activity

MIC
Antibacterial
5.0 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP

Other

Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The m
Evidence 3 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

C. glutamicum ATCC 13032

Source & Reference

dbAMP DRAMP

Other

nst Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set
Evidence 4 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

Staphylococcus aureus ATCC 9144

Source & Reference

dbAMP DRAMP

Other

.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set at the lowest concentration of peptid
Evidence 5 Activity

Activity

MIC
Antifungal
2.5 µM

Target

L. anguillarum serotype O2

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aur
Evidence 6 Activity

Activity

MIC
Antifungal
5.0 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The m
Evidence 7 Activity

Activity

MIC
Antifungal
2.5 µM

Target

C. glutamicum ATCC 13032

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

nst Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set
Evidence 8 Activity

Activity

MIC
Antifungal
2.5 µM

Target

Staphylococcus aureus ATCC 9144

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set at the lowest concentration of peptid
Evidence 9 Activity

Activity

MIC
Antiparasitic
2.5 µM

Target

L. anguillarum serotype O2

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aur
Evidence 10 Activity

Activity

MIC
Antiparasitic
5.0 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The m
Evidence 11 Activity

Activity

MIC
Antiparasitic
2.5 µM

Target

C. glutamicum ATCC 13032

Source & Reference

dbAMP 3.0 DRAMP

Other

nst Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set
Evidence 12 Activity

Activity

MIC
Antiparasitic
2.5 µM

Target

Staphylococcus aureus ATCC 9144

Source & Reference

dbAMP 3.0 DRAMP

Other

.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set at the lowest concentration of peptid
Evidence 13 Activity

Activity

MIC
Antiviral
2.5 µM

Target

L. anguillarum serotype O2

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aur
Evidence 14 Activity

Activity

MIC
Antiviral
5.0 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The m
Evidence 15 Activity

Activity

MIC
Antiviral
2.5 µM

Target

C. glutamicum ATCC 13032

Source & Reference

dbAMP 3.0 DRAMP

Other

nst Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set
Evidence 16 Activity

Activity

MIC
Antiviral
2.5 µM

Target

Staphylococcus aureus ATCC 9144

Source & Reference

dbAMP 3.0 DRAMP

Other

.5 uM), E. coli ATCC 25922 (MIC 5.0 uM), Gram+ C. glutamicum ATCC 13032 (MIC 2.5 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set at the lowest concentration of peptid
Evidence 17 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Strongylocins, novel antimicrobial peptides from the green sea urchin, Strongylocentrotus droebachiensis. | Dev Comp Immunol | 2008