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Peptide record

TPDB12183

Antibacterial Antifungal standard
47 amino acids
Basic Information
3D PDB MODEL
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TPDB12183
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 47-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RISKKKGKGSWIKNGLIKGIKGLGKEISLDVIRTGIDIAGCKIKGEC
Physicochemical Analysis
C222H391N65O61S2
QHMFPY
K
5011.07
10.52
12
4
15
+8
12.16
-0.217
107.87
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5625
112.25
7
Residue Composition
number
1
A
2
R
1
N
2
D
2
C
2
E
0
Q
9
G
0
H
9
I
3
L
10
K
0
M
0
F
0
P
3
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 1 D: 2 C: 2 E: 2 Q: 0 G: 9 H: 0 I: 9 L: 3 K: 10 M: 0 F: 0 P: 0 S: 3 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
47
C222H391N65O61S2
5011.07
10.52
+8
12.16
-0.217
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.6 µM

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus ATCC2592 (MIC 0.6 uM), B. licheniformis X39 (IS) (MIC 10uM), S. carnosus KHS (IS) (MIC 1.3 uM), R. rhodochrous
Evidence 2 Activity

Activity

MIC
Antibacterial
5 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

(IS) (MIC 10uM), S. carnosus KHS (IS) (MIC 1.3 uM), R. rhodochrous X15 (IS) (MIC 0.3 uM), E. coli ATCC 25922 (MIC 5 uM), S. rubidaea X01 (IS) (MIC 10 uM), P. faecalis X29 (IS) (MIC 0.6 uM), and C. albicans ATC
Evidence 3 Activity

Activity

MIC
Antibacterial
80 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP

Other

5922 (MIC 5 uM), S. rubidaea X01 (IS) (MIC 10 uM), P. faecalis X29 (IS) (MIC 0.6 uM), and C. albicans ATCC2002 (MIC 80 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
0.6 µM

Target

Staphylococcus aureus ATCC2592

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus ATCC2592 (MIC 0.6 uM), B. licheniformis X39 (IS) (MIC 10uM), S. carnosus KHS (IS) (MIC 1.3 uM), R. rhodochrous
Evidence 5 Activity

Activity

MIC
Antifungal
5 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(IS) (MIC 10uM), S. carnosus KHS (IS) (MIC 1.3 uM), R. rhodochrous X15 (IS) (MIC 0.3 uM), E. coli ATCC 25922 (MIC 5 uM), S. rubidaea X01 (IS) (MIC 10 uM), P. faecalis X29 (IS) (MIC 0.6 uM), and C. albicans ATC
Evidence 6 Activity

Activity

MIC
Antifungal
80 µM

Target

Candida albicans ATCC2002

Source & Reference

dbAMP CAFPdb Antifungipept

Other

5922 (MIC 5 uM), S. rubidaea X01 (IS) (MIC 10 uM), P. faecalis X29 (IS) (MIC 0.6 uM), and C. albicans ATCC2002 (MIC 80 uM).