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Peptide record

TPDB12176

Antibacterial Anticancer Antifungal Antiparasitic standard
47 amino acids
Basic Information
3D PDB MODEL
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TPDB12176
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 47-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
HSSGYTRPLRKPSRPIFIRPIGCDVCYGIPSSTARLCCFRYGDCCHL
Physicochemical Analysis
C231H362N70O62S6
NEQMW
RC
5304.21
8.87
9
2
14
+5
3.91
-0.153
66.38
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
4845
91.34
16
Residue Composition
number
1
A
6
R
0
N
2
D
6
C
0
E
0
Q
4
G
2
H
4
I
3
L
1
K
0
M
2
F
5
P
5
S
2
T
0
W
3
Y
1
V
Amino Acid Distribution
A: 1 R: 6 N: 0 D: 2 C: 6 E: 0 Q: 0 G: 4 H: 2 I: 4 L: 3 K: 1 M: 0 F: 2 P: 5 S: 5 T: 2 W: 0 Y: 3 V: 1
Chemical Descriptors
47
C231H362N70O62S6
5304.21
8.87
+5
3.91
-0.153
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.84-1.26 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Filamentous fungi F. oxysporum (MIC 0.84-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridan
Evidence 2 Activity

Activity

MIC
Antibacterial
4.38-6.57 µM

Target

B. cinerea

Source & Reference

dbAMP DRAMP

Other

Active against Filamentous fungi F. oxysporum (MIC 0.84-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus
Evidence 3 Activity

Activity

MIC
Antibacterial
1.26-1.9 µM

Target

P. crustosum

Source & Reference

dbAMP DRAMP

Other

against Filamentous fungi F. oxysporum (MIC 0.84-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus (MIC 1.9-2.92 uM), B-megaterium
Evidence 4 Activity

Activity

MIC
Antibacterial
1.9-2.92 µM

Target

A. viridans

Source & Reference

dbAMP DRAMP

Other

4-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus (MIC 1.9-2.92 uM), B-megaterium (MIC > 50 uM), S-aureus (MIC> 50 uM), Gram- E.
Evidence 5 Activity

Activity

MIC
Antibacterial
1.9-2.92 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP

Other

8-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus (MIC 1.9-2.92 uM), B-megaterium (MIC > 50 uM), S-aureus (MIC> 50 uM), Gram- E. coli 363 (MIC 22-33 uM), V-v
Evidence 6 Activity

Activity

MIC
Antibacterial
22-33 µM

Target

Escherichia coli 363

Source & Reference

dbAMP DRAMP

Other

M), M. luteus (MIC 1.9-2.92 uM), B-megaterium (MIC > 50 uM), S-aureus (MIC> 50 uM), Gram- E. coli 363 (MIC 22-33 uM), V-vulnificus (MIC>50 uM), S-thyphimurium (MIC>50 uM), and K-pneumoniae (MIC>50 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
0.84-1.26 µM

Target

F. oxysporum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Filamentous fungi F. oxysporum (MIC 0.84-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridan
Evidence 8 Activity

Activity

MIC
Antifungal
4.38-6.57 µM

Target

B. cinerea

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against Filamentous fungi F. oxysporum (MIC 0.84-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus
Evidence 9 Activity

Activity

MIC
Antifungal
1.26-1.9 µM

Target

P. crustosum

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

against Filamentous fungi F. oxysporum (MIC 0.84-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus (MIC 1.9-2.92 uM), B-megaterium
Evidence 10 Activity

Activity

MIC
Antifungal
1.9-2.92 µM

Target

A. viridans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

4-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus (MIC 1.9-2.92 uM), B-megaterium (MIC > 50 uM), S-aureus (MIC> 50 uM), Gram- E.
Evidence 11 Activity

Activity

MIC
Antifungal
1.9-2.92 µM

Target

M. luteus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

8-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus (MIC 1.9-2.92 uM), B-megaterium (MIC > 50 uM), S-aureus (MIC> 50 uM), Gram- E. coli 363 (MIC 22-33 uM), V-v
Evidence 12 Activity

Activity

MIC
Antifungal
22-33 µM

Target

Escherichia coli 363

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

M), M. luteus (MIC 1.9-2.92 uM), B-megaterium (MIC > 50 uM), S-aureus (MIC> 50 uM), Gram- E. coli 363 (MIC 22-33 uM), V-vulnificus (MIC>50 uM), S-thyphimurium (MIC>50 uM), and K-pneumoniae (MIC>50 uM).
Evidence 13 Activity

Activity

MIC
Antiparasitic
0.84-1.26 µM

Target

F. oxysporum

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Filamentous fungi F. oxysporum (MIC 0.84-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridan
Evidence 14 Activity

Activity

MIC
Antiparasitic
4.38-6.57 µM

Target

B. cinerea

Source & Reference

DRAMP

Other

Active against Filamentous fungi F. oxysporum (MIC 0.84-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus
Evidence 15 Activity

Activity

MIC
Antiparasitic
1.26-1.9 µM

Target

P. crustosum

Source & Reference

DRAMP

Other

against Filamentous fungi F. oxysporum (MIC 0.84-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus (MIC 1.9-2.92 uM), B-megaterium
Evidence 16 Activity

Activity

MIC
Antiparasitic
1.9-2.92 µM

Target

A. viridans

Source & Reference

DRAMP

Other

4-1.26 uM), B. cinerea (MIC 4.38-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus (MIC 1.9-2.92 uM), B-megaterium (MIC > 50 uM), S-aureus (MIC> 50 uM), Gram- E.
Evidence 17 Activity

Activity

MIC
Antiparasitic
1.9-2.92 µM

Target

M. luteus

Source & Reference

DRAMP

Other

8-6.57 uM), P. crustosum (MIC 1.26-1.9 uM), bacteria Gram+ A. viridans (MIC 1.9-2.92 uM), M. luteus (MIC 1.9-2.92 uM), B-megaterium (MIC > 50 uM), S-aureus (MIC> 50 uM), Gram- E. coli 363 (MIC 22-33 uM), V-v
Evidence 18 Activity

Activity

MIC
Antiparasitic
22-33 µM

Target

Escherichia coli 363

Source & Reference

DRAMP

Other

M), M. luteus (MIC 1.9-2.92 uM), B-megaterium (MIC > 50 uM), S-aureus (MIC> 50 uM), Gram- E. coli 363 (MIC 22-33 uM), V-vulnificus (MIC>50 uM), S-thyphimurium (MIC>50 uM), and K-pneumoniae (MIC>50 uM).