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Peptide record

TPDB12173

Antibacterial Anticancer Antifungal Antiparasitic standard
47 amino acids
Basic Information
3D PDB MODEL
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TPDB12173
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 Antifungipept i2APP
standard
No
A 47-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
LLGRCKVKSNRFHGPCLTDTHCSTVCRGEGYKGGDCHGLRRRCMCLC
Physicochemical Analysis
C213H353N75O61S9
AQIW
C
5229.15
8.75
12
3
10
+6
9.93
-0.417
53.83
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1990
38.06
15
Residue Composition
number
0
A
6
R
1
N
2
D
8
C
1
E
0
Q
7
G
3
H
0
I
5
L
3
K
1
M
1
F
1
P
2
S
3
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 6 N: 1 D: 2 C: 8 E: 1 Q: 0 G: 7 H: 3 I: 0 L: 5 K: 3 M: 1 F: 1 P: 1 S: 2 T: 3 W: 0 Y: 1 V: 2
Chemical Descriptors
47
C213H353N75O61S9
5229.15
8.75
+6
9.93
-0.417
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli, P. aeruginosa, and E. hirae. Warning: Note that the material used for antimicrobial activity assays contains both fabatin-1 and fabatin-2, which differ only at residue 13, N for fabatin-1 and H for fabatin-2. It's unclear whether these two very closely related fabatins differ in antimicrobial activity. Updated 12/2017 7/2021.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli, P. aeruginosa, and E. hirae. Warning: Note that the material used for antimicrobial activity assays contains both fabatin-1 and fabatin-2, which differ only at residue 13, N for fabatin-1 and H for fabatin-2. It's unclear whether these two very closely related fabatins differ in antimicrobial activity. Updated 12/2017 7/2021.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against E. coli, P. aeruginosa, and E. hirae. Warning: Note that the material used for antimicrobial activity assays contains both fabatin-1 and fabatin-2, which differ only at residue 13, N for fabatin-1 and H for fabatin-2. It's unclear whether these two very closely related fabatins differ in antimicrobial activity. Updated 12/2017 7/2021.