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Peptide record

TPDB12167

Antibacterial Antifungal standard
47 amino acids
Basic Information
3D PDB MODEL
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TPDB12167
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 47-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
RSPPQCQYTNCAAVLCPAVYCANAYTPPCGCCDICPPQKYGGGYRPR
Physicochemical Analysis
C216H328N62O63S8
EHMFW
CP
5057.84
8.09
4
1
14
+3
3.08
-0.336
39.57
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
7950
157.18
21
Residue Composition
number
5
A
3
R
2
N
1
D
8
C
0
E
3
Q
4
G
0
H
1
I
1
L
1
K
0
M
0
F
8
P
1
S
2
T
0
W
5
Y
2
V
Amino Acid Distribution
A: 5 R: 3 N: 2 D: 1 C: 8 E: 0 Q: 3 G: 4 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 8 S: 1 T: 2 W: 0 Y: 5 V: 2
Chemical Descriptors
47
C216H328N62O63S8
5057.84
8.09
+3
3.08
-0.336
Evidence Records 20 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>100 µM

Target

E.coli

Source & Reference

NA

Other

e against marine bacteria, but weakly in vitro. Activity tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine L.anguillarum (MIC >100 uM), A.salmonicida (MIC >100
Evidence 2 Activity

Activity

MIC
Antibacterial
>100 µM

Target

P.aeruginosa

Source & Reference

NA

Other

ria, but weakly in vitro. Activity tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine L.anguillarum (MIC >100 uM), A.salmonicida (MIC >100 uM), Gram+ terrestrial C.glu
Evidence 3 Activity

Activity

MIC
Antibacterial
>100 µM

Target

L.anguillarum

Source & Reference

NA

Other

tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine L.anguillarum (MIC >100 uM), A.salmonicida (MIC >100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC
Evidence 4 Activity

Activity

MIC
Antibacterial
>100 µM

Target

A.salmonicida

Source & Reference

NA

Other

ial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine L.anguillarum (MIC >100 uM), A.salmonicida (MIC >100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum
Evidence 5 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

C.glutamicum

Source & Reference

NA

Other

0 uM), marine L.anguillarum (MIC >100 uM), A.salmonicida (MIC >100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. diverge
Evidence 6 Activity

Activity

MIC
Antibacterial
>100 µM

Target

S.aureus

Source & Reference

NA

Other

(MIC >100 uM), A.salmonicida (MIC >100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. divergens (MIC 50 uM), and C. f
Evidence 7 Activity

Activity

MIC
Antibacterial
50 µM

Target

C. maltaromaticum

Source & Reference

NA

Other

cida (MIC >100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. divergens (MIC 50 uM), and C. funditum (MIC 25 uM). It remains
Evidence 8 Activity

Activity

MIC
Antibacterial
50 µM

Target

C. mobile

Source & Reference

NA

Other

strial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. divergens (MIC 50 uM), and C. funditum (MIC 25 uM). It remains to be tested whether t
Evidence 9 Activity

Activity

MIC
Antibacterial
50 µM

Target

C. divergens

Source & Reference

NA

Other

C 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. divergens (MIC 50 uM), and C. funditum (MIC 25 uM). It remains to be tested whether the peptide is more active
Evidence 10 Activity

Activity

MIC
Antibacterial
25 µM

Target

C. funditum

Source & Reference

NA

Other

uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. divergens (MIC 50 uM), and C. funditum (MIC 25 uM). It remains to be tested whether the peptide is more active at low temperature where the
Evidence 11 Activity

Activity

MIC
Antifungal
>100 µM

Target

E.coli

Source & Reference

Antifungipept

Other

e against marine bacteria, but weakly in vitro. Activity tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine L.anguillarum (MIC >100 uM), A.salmonicida (MIC >100
Evidence 12 Activity

Activity

MIC
Antifungal
>100 µM

Target

P.aeruginosa

Source & Reference

Antifungipept

Other

ria, but weakly in vitro. Activity tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine L.anguillarum (MIC >100 uM), A.salmonicida (MIC >100 uM), Gram+ terrestrial C.glu
Evidence 13 Activity

Activity

MIC
Antifungal
>100 µM

Target

L.anguillarum

Source & Reference

Antifungipept

Other

tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine L.anguillarum (MIC >100 uM), A.salmonicida (MIC >100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC
Evidence 14 Activity

Activity

MIC
Antifungal
>100 µM

Target

A.salmonicida

Source & Reference

Antifungipept

Other

ial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine L.anguillarum (MIC >100 uM), A.salmonicida (MIC >100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum
Evidence 15 Activity

Activity

MIC
Antifungal
12.5 µM

Target

C.glutamicum

Source & Reference

Antifungipept

Other

0 uM), marine L.anguillarum (MIC >100 uM), A.salmonicida (MIC >100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. diverge
Evidence 16 Activity

Activity

MIC
Antifungal
>100 µM

Target

S.aureus

Source & Reference

Antifungipept

Other

(MIC >100 uM), A.salmonicida (MIC >100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. divergens (MIC 50 uM), and C. f
Evidence 17 Activity

Activity

MIC
Antifungal
50 µM

Target

C. maltaromaticum

Source & Reference

Antifungipept

Other

cida (MIC >100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. divergens (MIC 50 uM), and C. funditum (MIC 25 uM). It remains
Evidence 18 Activity

Activity

MIC
Antifungal
50 µM

Target

C. mobile

Source & Reference

Antifungipept

Other

strial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. divergens (MIC 50 uM), and C. funditum (MIC 25 uM). It remains to be tested whether t
Evidence 19 Activity

Activity

MIC
Antifungal
50 µM

Target

C. divergens

Source & Reference

Antifungipept

Other

C 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. divergens (MIC 50 uM), and C. funditum (MIC 25 uM). It remains to be tested whether the peptide is more active
Evidence 20 Activity

Activity

MIC
Antifungal
25 µM

Target

C. funditum

Source & Reference

Antifungipept

Other

uM), C. maltaromaticum (MIC 50 uM), C. mobile (MIC 50 uM), C. divergens (MIC 50 uM), and C. funditum (MIC 25 uM). It remains to be tested whether the peptide is more active at low temperature where the