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Peptide record

TPDB12158

Antibacterial Anticancer Antifungal Antiparasitic standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB12158
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 46-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
AAKPMGITCDLLSLWKVGHAACAAHCLVLGDVGGYCTKEGLCVCKE
Physicochemical Analysis
C205H333N55O59S7
RNQF
ACGL
4736.65
6.91
6
4
20
-0
4.43
0.596
97.61
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
7365
155.49
10
Residue Composition
number
6
A
0
R
0
N
2
D
6
C
2
E
0
Q
6
G
2
H
1
I
6
L
4
K
1
M
0
F
1
P
1
S
2
T
1
W
1
Y
4
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 2 C: 6 E: 2 Q: 0 G: 6 H: 2 I: 1 L: 6 K: 4 M: 1 F: 0 P: 1 S: 1 T: 2 W: 1 Y: 1 V: 4
Chemical Descriptors
46
C205H333N55O59S7
4736.65
6.91
-0
4.43
0.596
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
The HPLC fraction gave no activity at 8 uM. In the assay with lysozyme, however, it gave activity equivalent to 2.5 uM cecropin B, implying mainly a synegistic effect on E. coli (synergy:AMPs).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
The HPLC fraction gave no activity at 8 uM. In the assay with lysozyme, however, it gave activity equivalent to 2.5 uM cecropin B, implying mainly a synegistic effect on E. coli (synergy:AMPs).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

The HPLC fraction gave no activity at 8 uM. In the assay with lysozyme, however, it gave activity equivalent to 2.5 uM cecropin B, implying mainly a synegistic effect on E. coli (synergy:AMPs).