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Peptide record

TPDB12147

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB12147
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 46-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIFSKISGKAIKNLFIKGAKNVGKRVGMDVVRTGMDVVGCKIKGEC
Physicochemical Analysis
C213H368N62O58S4
QHPWY
GK
4853.89
10.52
10
3
18
+7
10.11
0.137
93.04
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
2.58
7
Residue Composition
number
2
A
2
R
2
N
2
D
2
C
1
E
0
Q
8
G
0
H
5
I
1
L
8
K
2
M
2
F
0
P
2
S
1
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 2 R: 2 N: 2 D: 2 C: 2 E: 1 Q: 0 G: 8 H: 0 I: 5 L: 1 K: 8 M: 2 F: 2 P: 0 S: 2 T: 1 W: 0 Y: 0 V: 6
Chemical Descriptors
46
C213H368N62O58S4
4853.89
10.52
+7
10.11
0.137
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
5.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram- bacteria E. coli (MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 2 Activity

Activity

MIC
Antibacterial
11 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Updated 7/2021
Evidence 3 Activity

Activity

MIC
Antibacterial
11.0 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP

Other

alled P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Updated 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
5.5 µg/mL

Target

Escherichia coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram- bacteria E. coli (MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 5 Activity

Activity

MIC
Antifungal
11 µg/mL

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Updated 7/2021
Evidence 6 Activity

Activity

MIC
Antifungal
11.0 µg/mL

Target

Candida albicans

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

alled P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Updated 7/2021
Evidence 7 Activity

Activity

MIC
Antiparasitic
5.5 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram- bacteria E. coli (MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 8 Activity

Activity

MIC
Antiparasitic
11 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Updated 7/2021
Evidence 9 Activity

Activity

MIC
Antiparasitic
11.0 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Updated 7/2021
Evidence 10 Activity

Activity

MIC
Antiviral
5.5 µg/mL

Target

Escherichia coli

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against Gram- bacteria E. coli (MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC
Evidence 11 Activity

Activity

MIC
Antiviral
11 µg/mL

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

MIC 5.5 ug/ml), B. pyocyaneus (now called P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Updated 7/2021
Evidence 12 Activity

Activity

MIC
Antiviral
11.0 µg/mL

Target

Candida albicans

Source & Reference

DRAMP

Other

alled P. aeruginosa) (MIC 11.0 ug/ml), Gram+ bacteria S. aureus (MIC 11 ug/ml), and yeast C. albicans (MIC 11.0 ug/ml). Updated 7/2021