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Peptide record

TPDB12145

Antibacterial Anticancer Antifungal Antiparasitic standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB12145
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 46-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
EVERKHPLGGSRPGRCPTVPPGTFGHCACLCTGDASEPKGQKCCSN
Physicochemical Analysis
C196H316N64O63S6
IMWY
G
4769.42
8.03
8
4
7
+2
15.30
-0.698
33.91
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
375
7.86
14
Residue Composition
number
2
A
3
R
1
N
1
D
6
C
3
E
1
Q
7
G
2
H
0
I
2
L
3
K
0
M
1
F
6
P
3
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 3 N: 1 D: 1 C: 6 E: 3 Q: 1 G: 7 H: 2 I: 0 L: 2 K: 3 M: 0 F: 1 P: 6 S: 3 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
46
C196H316N64O63S6
4769.42
8.03
+2
15.30
-0.698
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
After 2 h incubation with 200 ug/ml peptide, log10 CFU reduction for S. zooepidemicus (1.7 reduction by 94.0%), E. coli (1.42, 90.2%), P. aeruginosa (0.95, 77.6% reduction), K.pneumoniae (no change). Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
After 2 h incubation with 200 ug/ml peptide, log10 CFU reduction for S. zooepidemicus (1.7 reduction by 94.0%), E. coli (1.42, 90.2%), P. aeruginosa (0.95, 77.6% reduction), K.pneumoniae (no change). Updated 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

After 2 h incubation with 200 ug/ml peptide, log10 CFU reduction for S. zooepidemicus (1.7 reduction by 94.0%), E. coli (1.42, 90.2%), P. aeruginosa (0.95, 77.6% reduction), K.pneumoniae (no change). Updated 7/2021